Amish, Mennonite, and Hutterite
Genetic Disorder Database

Adducted Thumbs Syndrome

Disorder
OMIM #: %201550  (Click to access OMIM database)
Disorder: Adducted Thumbs Syndrome 
Also known as: THUMBS, CONGENITAL CLASPED 
Clinical
Phenotype: cleft palate, high-arched palate, contractures, craniosynostosis, microcephaly, thumbs flexed and adducted, swallowing difficulties, feeding difficulties, respiratory distress, hypotonia, hypertrichosis, myopathy 
Seen In: Amish
Old Order Mennonite
Old Colony Mennonite
Unknown/Other Mennonite
Hutterite
Remarks: Autosomal recessive 
Mutations
Unknown
Last updated: 2022-11-01 

References
Christian JC, Andrews PA, Conneally PM, and Muller J. (1971) The adducted thumbs syndrome. An autosomal recessive disease with arthrogryposis, dysmyelination, craniostenosis, and cleft palate. Clin Genet 2(2): 95-103.
PubMed ID: 5116596 

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