Amish, Mennonite, and Hutterite
Genetic Disorder Database

Hashimoto Thyroiditis

Disorder
OMIM #: %140300  (Click to access OMIM database)
Disorder: Hashimoto Thyroiditis 
Also known as: HT, HASHIMOTO STRUMA, HYPOTHYROIDISM, AUTOIMMUNE, THYROID AUTOANTIBODIES, INCLUDED 
Clinical
Phenotype: Thyroid autoimmunity, female predominance, hypothyroidism 
Seen In: Amish
Old Order Mennonite
Old Colony Mennonite
Unknown/Other Mennonite
Hutterite
Remarks:  
Mutations
1   Amish  
Gene: 5q11.2-q14.3
Base Change:
Amino Acid Change:
Last updated: 2018-10-12 

References
Allen EM, Hsueh WC, Sabra MM, Pollin TI, Ladenson PW, Silver KD, Mitchell BD, Shuldiner AR. (2003) A genome-wide scan for autoimmune thyroiditis in the Old Order Amish: replication of genetic linkage on chromosome 5q11.2-q14.3. J Clin Endocrinol Metab 88(3): 1292-1296.
PubMed ID: 12629121 
Pauls DL, Zakarija M, McKenzie JM, Egeland JA. (1993) Complex segregation analysis of antibodies to thyroid peroxidase in Old Order Amish families. Am J Med Genet Sep 1;47(3):375-9.
PubMed ID: 8135284 

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